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Description

Vitamin B12 is reduced to cobalamin regardless of form (cyan-, methyl-, adenosyl-, hydroxo-) then re-assembled as methylcoblamin by MS for use in the cytosol, or adenosylcobalamin by MM for use in the mitochondria

2023;61(1):doi:10.1128/jcm.01110-22 45

Among these discoveries, MOTS-C became one of the most extensively investigated peptides because of its unique mitochondrial origin and its relevance within experimental models studying cellular metabolism, mitochondrial communication and biochemical regulation